PATIENT-REPORTED OUTCOMES OF KINEMATIC VS MECHANICAL ALIGNMENT IN TOTAL KNEE ARTHROPLASTY: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS

Patient-Reported Outcomes of Kinematic vs Mechanical Alignment in Total Knee Arthroplasty: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Background: Total knee arthroplasty (TKA) is an effective treatment method for severe osteoarthritis of the knee.Poor alignment of a knee replacement has been associated with suboptimal clinical results.Traditionally, mechanical alignment (MA) moen rothbury faucet has been considered the gold standard.In light of reports of decreased satisfaction w

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Human neural stem cells directly programmed from peripheral blood show functional integration into the adult mouse brain

Abstract Transplantation of induced pluripotent stem cell-derived neural cells represents a promising strategy for treating neurodegenerative diseases.However, reprogramming of somatic cells and their subsequent neural differentiation is complex and time-consuming, thereby impeding autologous applications.Recently, direct transcription factor-based

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Antidepressant induced excessive yawning and indifference

Introduction Antidepressant induced excessive yawning has been described as a possible side effect of pharmacotherapy.A syndrome of indifference has also been described as another possible side effect.The frequency of those phenomena and their physiopathology are unknown.They are both considered benign and reversible after antidepressant discontinu

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